Neural replay as context-driven memory reactivation
Zhenglong Zhou, Michael Kahana, Anna Schapiro, University of Pennsylvania, United States
Posters 2 Poster
Pacific Ballroom H-O
Fri, 26 Aug, 19:30 - 21:30 Pacific Time (UTC -7)
Replay in the brain is not a simple recapitulation of recent experience, with awake replay often unrolling in reverse temporal order upon receipt of reward, in a manner dependent on reward magnitude. These findings have led to the proposal that replay serves to update values in accordance with reinforcement learning theories. We offer a more parsimonious account of these observations, suggesting that animals associate experiences with the contexts in which they are encoded, in a manner modulated by the salience of each experience. During periods of quiescence, replay emerges when contextual cues trigger a cascade of reactivations driven by the reinstatement of each memory’s encoding context. Our theory unifies numerous replay phenomena, including findings that existing models fail to capture.